LINC00881

Across TCGA pan-cancer cohorts, LINC00881 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated LINC00881 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LINC00881 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC00881 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UVM show a favorable association.

LUAD, UVM, and SKCM are the cancer types where LINC00881 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	III,IV	0.474	0.118	<.001	70	view →
UVM	OS	Quartile	II,III,IV	0.948	0.405	<.001	50	view →
SKCM	OS	Median	IV	0.739	0.146	.002	43	view →
BRCA	OS	Median	II,III,IV	0.682	0.494	<.001	34	view →
THYM	DFS	Tertile	All	0.596	1.000	.001	32	view →
LGG	DFS	Quartile	All	0.655	0.814	.001	32	view →
COAD	DFS	Tertile	All	0.557	0.809	<.001	26	view →
KIRC	DFS	Quartile	All	0.497	0.753	<.001	24	view →
ACC	DFS	Quartile	II,III,IV	0.450	0.686	.013	22	view →
KIRP	DFS	Quartile	All	0.946	0.815	.004	18	view →
KICH	DFS	Quartile	All	0.425	0.916	.025	12	view →
READ	DFS	Tertile	IV	0.348	0.882	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

LINC00881–LUAD (DFS)

Open the LUAD breakdown →