LINC00880

Across TCGA patient cohorts, LINC00880 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,127 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LINC00880-associated GO terms across cancer lineages are Negative regulation of response to endoplasmic reticulum stress, Tissue remodeling, and Positive regulation of protein-containing complex assembly. Each is linked with LINC00880 in more than 17 cancer types. Because this analysis shows association rather than direction, both LINC00880-to-partner and partner-to-LINC00880 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of response to endoplasmic reticulum stress grouped by LINC00880-low versus LINC00880-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00880→partner) and Y-score (partner→LINC00880) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of response to endoplasmic reticulum stress →	+0.054	+0.126	<.001	.003	2	17
ESCA	Tissue remodeling →	+0.043	+0.118	<.001	<.001	3	16
STAD	Positive regulation of protein-containing complex assembly →	+0.041	+0.092	<.001	<.001	3	16
KIRC	Fc receptor mediated stimulatory signaling pathway →	+0.048	+0.109	<.001	<.001	3	16
ESCA	Response to endoplasmic reticulum stress →	+0.041	+0.127	<.001	<.001	3	16
STAD	Positive regulation of canonical NF-kappaB signal transduction →	+0.042	+0.078	<.001	.004	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,127 associations by consensus.

Negative regulation of response to endoplasmic reticulum stress by LINC00880 expression — ESCA

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