Across TCGA pan-cancer cohorts, LINC00700 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC00700’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC00700 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00700 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA and KIRC are the cancer types where LINC00700 tumor–normal differential expression is most reproducible.