Across TCGA pan-cancer cohorts, LINC00685 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LINC00685 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00685 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00685 expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.
KIRC, SKCM, and LIHC are the cancer types where LINC00685 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.