LINC00683

Across TCGA pan-cancer cohorts, LINC00683 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00683’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC00683 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00683 is over-expressed in tumor, although a few such as LIHC and KIRC show the opposite, repressed pattern.

LIHC, KIRC, and THCA are the cancer types where LINC00683 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00683 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	II,III,IV	−0.145	<.001	9	view →
KIRC	Male	III,IV	−0.079	<.001	9	view →
THCA	Male	All	−0.471	<.001	8	view →
KICH	All	All	−0.087	.002	8	view →
BLCA	All	All	−0.138	.013	3	view →
PRAD	All	All	−0.582	<.001	2	view →
LUSC	All	III,IV	−0.260	<.001	2	view →
BRCA	All	III,IV	+0.220	.044	2	view →
KIRP	All	All	−0.056	.005	2	view →
LUSC	All	All	+0.109	.028	1	view →
READ	Female	All	−0.066	.002	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

LINC00683–LIHC

Open the LIHC breakdown →