LINC00681

Across TCGA pan-cancer cohorts, LINC00681 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated LINC00681 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher LINC00681 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00681 expression acts as an unfavorable survival marker, although some lineages such as UVM and BLCA show a favorable association.

LIHC, READ, and UCS are the cancer types where LINC00681 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	III,IV	0.123	0.624	<.001	99	view →
READ	OS	Tertile	All	0.111	0.909	<.001	90	view →
UCS	OS	Tertile	III,IV	0.278	0.669	<.001	66	view →
COAD	DFS	Tertile	All	0.443	0.788	.002	54	view →
UVM	DFS	Quartile	All	0.958	0.544	.001	33	view →
ACC	DFS	Tertile	II,III,IV	0.050	0.595	<.001	33	view →
CHOL	OS	Tertile	All	0.200	0.740	.002	27	view →
SARC	DFS	Tertile	All	0.488	0.638	.003	21	view →
KIRC	DFS	Tertile	IV	0.205	0.603	.001	18	view →
THCA	OS	Tertile	All	0.654	0.960	.006	18	view →
THYM	OS	Median	All	0.812	1.000	.020	14	view →
BLCA	OS	Tertile	II,III,IV	1.000	0.414	.044	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

LINC00681–LIHC (OS)

Open the LIHC breakdown →