LINC00678

Across TCGA pan-cancer cohorts, LINC00678 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC00678 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher LINC00678 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00678 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUAD show a favorable association.

LUSC, BRCA, and THCA are the cancer types where LINC00678 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
BRCA	OS	Tertile	III,IV	0.711	0.497	.011	33	view →
THCA	DFS	Tertile	IV	0.244	0.835	.007	30	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	27	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
LUAD	OS	Tertile	III,IV	1.000	0.240	.012	18	view →
ACC	DFS	Tertile	All	0.125	0.558	.017	18	view →
READ	DFS	Tertile	IV	0.112	0.811	.008	18	view →
UCEC	DFS	Tertile	IV	0.298	0.717	.021	18	view →
OV	OS	Median	II,III,IV	0.356	0.289	.030	10	view →
PAAD	OS	Tertile	All	0.220	0.474	.036	9	view →
THYM	OS	Tertile	II,III,IV	0.700	0.960	.025	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC00678–LUSC (OS)

Open the LUSC breakdown →