LINC00677

Across TCGA pan-cancer cohorts, LINC00677 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC00677’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC00677 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00677 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

STAD, KICH, and THCA are the cancer types where LINC00677 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00677 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.362	<.001	7	view →
KICH	All	All	−0.296	.002	6	view →
THCA	All	All	+0.187	<.001	5	view →
COAD	Male	All	−0.127	.008	5	view →
UCEC	All	II,III,IV	+0.520	.012	4	view →
HNSC	All	All	+0.086	.003	4	view →
CHOL	All	All	+0.461	.003	2	view →
LIHC	All	All	+0.134	.007	2	view →
LUAD	All	III,IV	−0.204	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC00677–STAD

Open the STAD breakdown →