LINC00672

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00672 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC00672’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC00672 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00672 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, THCA, and UCEC are the cancer types where LINC00672 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00672 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHFemaleAll−0.758<.0019view →
THCAMaleIV+0.503<.0019view →
UCECAllIII,IV−2.237<.0018view →
LUSCAllII,III,IV−0.538<.0018view →
KIRCMaleAll+0.385<.0018view →
LIHCFemaleAll+0.355<.0018view →
BLCAAllAll−0.736.0017view →
CHOLAllAll+1.881<.0015view →
PRADAllAll−0.956<.0012view →
COADAllIII,IV−0.388.0292view →
KIRPAllIV+0.347.0242view →
STADAllAll−0.372.0461view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC00672–KICH

Tumor-vs-normal expression box plot for LINC00672 RNA in KICH.

Open the KICH breakdown →

Exploration