LINC00652

Across TCGA pan-cancer cohorts, LINC00652 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC00652’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC00652 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00652 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and KICH are the cancer types where LINC00652 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00652 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.718	<.001	11	view →
KIRC	Male	All	−0.535	<.001	11	view →
KICH	Male	All	−0.779	<.001	10	view →
UCEC	All	III,IV	−0.370	<.001	6	view →
CHOL	All	All	+0.348	<.001	5	view →
LUSC	All	All	+0.197	<.001	4	view →
BLCA	Female	III,IV	+0.180	.009	3	view →
KIRP	Male	All	−0.368	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC00652–THCA

Open the THCA breakdown →