Across TCGA pan-cancer cohorts, LINC00643 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC00643 data layer compared with 1 for mutation status.
The strongest signal is observed in uveal melanoma (UVM), where higher LINC00643 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00643 expression acts as an unfavorable survival marker, although some lineages such as LGG and PAAD show a favorable association.
UVM, ACC, and MESO are the cancer types where LINC00643 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.