LINC00642

Across TCGA pan-cancer cohorts, LINC00642 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00642’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00642 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00642 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and HNSC are the cancer types where LINC00642 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00642 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.108	<.001	6	view →
KICH	All	All	−0.230	.002	5	view →
HNSC	All	All	+0.049	.028	5	view →
LUAD	Female	II,III,IV	−0.053	.015	4	view →
COAD	Male	II,III,IV	−0.027	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC00642–KIRC

Open the KIRC breakdown →