LINC00641

Across TCGA pan-cancer cohorts, LINC00641 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC00641’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LINC00641 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00641 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

BLCA, THCA, and UCEC are the cancer types where LINC00641 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00641 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−2.082	<.001	10	view →
THCA	All	II,III,IV	−0.892	<.001	9	view →
UCEC	All	All	−1.403	<.001	8	view →
LUSC	Female	All	−1.418	<.001	7	view →
LUAD	All	II,III,IV	−0.831	<.001	7	view →
COAD	All	All	−0.584	<.001	7	view →
BRCA	All	III,IV	−1.419	<.001	6	view →
KIRP	Male	All	−0.676	<.001	6	view →
LIHC	All	All	+0.307	<.001	6	view →
CHOL	All	All	+1.526	<.001	5	view →
READ	Female	All	−1.472	.005	2	view →
PRAD	All	All	−0.574	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC00641–BLCA

Open the BLCA breakdown →