LINC00639

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00639 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00639-associated genes across cancer lineages are RNU6-1169P, OR13C3, and MIR708. Each is linked with LINC00639 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00639-to-partner and partner-to-LINC00639 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1169P grouped by LINC00639-low versus LINC00639-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00639→partner) and Y-score (partner→LINC00639) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNU6-1169P →+0.425+5.947<.001<.00131
SKCMOR13C3 →+0.035+5.080<.001.00431
SKCMMIR708 →+0.548+4.563<.001.00431
SKCMRN7SKP286 →+0.129+6.810<.001<.00131
SKCMATP5MFP1 →+0.245+4.595<.001.00431
SKCMOR5K1 →+0.036+5.797<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

RNU6-1169P by LINC00639 expression — SKCM

Box plot of RNU6-1169P in LINC00639-low vs LINC00639-high samples in SKCM.

Explore this box plot interactively →

Exploration