LINC00636

Across TCGA pan-cancer cohorts, LINC00636 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC00636 data layer compared with 1 for mutation status.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LINC00636 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00636 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

CESC, LGG, and LIHC are the cancer types where LINC00636 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	III,IV	0.400	0.948	<.001	72	view →
LGG	OS	Tertile	All	0.836	0.942	<.001	35	view →
LIHC	DFS	Tertile	III,IV	0.192	0.371	.009	33	view →
ACC	OS	Quartile	All	0.268	0.837	.002	28	view →
PAAD	OS	Tertile	II,III,IV	0.661	0.339	.017	17	view →
KICH	OS	Median	III,IV	0.178	0.847	<.001	14	view →
HNSC	OS	Median	All	0.769	0.643	.027	11	view →
KIRC	DFS	Median	II,III,IV	0.408	0.617	.009	10	view →
MESO	DFS	Median	IV	0.545	0.230	.013	9	view →
READ	DFS	Quartile	II,III,IV	0.609	0.871	.014	9	view →
ESCA	DFS	Quartile	III,IV	0.595	0.237	.017	9	view →
UCEC	DFS	Tertile	All	0.495	0.685	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC00636–CESC (DFS)

Open the CESC breakdown →