Across TCGA pan-cancer cohorts, LINC00632 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC00632’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00632 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00632 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
KIRC, LUAD, and BRCA are the cancer types where LINC00632 tumor–normal differential expression is most reproducible.