Across TCGA pan-cancer cohorts, LINC00616 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC00616’s most consistent transcriptional readouts.
The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where LINC00616 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00616 is over-expressed in tumor.
PAAD and UCEC are the cancer types where LINC00616 tumor–normal differential expression is most reproducible.