Across TCGA pan-cancer cohorts, LINC00613 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC00613’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC00613 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00613 is over-expressed in tumor, although a few such as PRAD and KIRC show the opposite, repressed pattern.
BRCA, PRAD, and KIRC are the cancer types where LINC00613 tumor–normal differential expression is most reproducible.