LINC00603

Across TCGA pan-cancer cohorts, LINC00603 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LINC00603 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC00603 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00603 expression acts as an unfavorable survival marker, although some lineages such as PAAD and STAD show a favorable association.

HNSC, LIHC, and BLCA are the cancer types where LINC00603 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.633	0.778	<.001	108	view →
LIHC	DFS	Tertile	II,III,IV	0.105	0.484	<.001	45	view →
BLCA	DFS	Tertile	All	0.496	0.646	.011	42	view →
OV	OS	Tertile	IV	0.206	0.789	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
READ	DFS	Tertile	IV	0.027	0.636	<.001	21	view →
ACC	OS	Tertile	All	0.154	0.702	.025	18	view →
PAAD	OS	Tertile	All	0.681	0.423	.036	6	view →
KIRP	OS	Tertile	All	0.432	0.701	.035	6	view →
STAD	DFS	Tertile	III,IV	0.552	0.284	.035	5	view →
THYM	DFS	Tertile	All	0.798	0.937	.042	3	view →
SARC	OS	Tertile	All	0.915	0.794	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

LINC00603–HNSC (OS)

Open the HNSC breakdown →