LINC00601

Across TCGA pan-cancer cohorts, LINC00601 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC00601’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00601 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00601 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, BLCA, and LUAD are the cancer types where LINC00601 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00601 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.296	<.001	11	view →
BLCA	All	All	+0.145	<.001	9	view →
LUAD	Female	All	+0.223	<.001	6	view →
BRCA	All	All	−0.122	.001	6	view →
LIHC	All	All	+0.221	.027	2	view →
LUSC	All	All	+0.191	.006	2	view →
THCA	All	All	+0.041	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC00601–HNSC

Open the HNSC breakdown →