Q-omics provides the consensus-scored LINC00598 profile across patient tissues and cancer cell-line models. LINC00598 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in LGG. Among the 18 cancer types available for tumor–normal comparison, LINC00598 is differentially expressed in 11, with the highest sampling consensus in KIRP. Additionally, LINC00598 RNA expression shows 17,708 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight LGG, KIRP, and UVM as cancer lineages where LINC00598 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00598 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00598 survival associations across molecular data types. LINC00598 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00598 RNA expression–survival associations across cancer types. High LINC00598 expression shows unfavorable associations in LGG, CESC, THCA, LUSC and LUAD, but favorable associations in SARC. The LGG Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LGG as the clearest survival context for LINC00598 RNA expression.
This table summarizes LINC00598 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00598. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00598 shows lower tumor expression in KIRP, THCA, BRCA and KIRC and higher tumor expression in KICH and CHOL. The KIRP box plot shows higher LINC00598 RNA expression in normal versus tumor tissue (log2 FC = −0.202, t-test p < 0.001).
This table shows molecular features associated with LINC00598 in patient tissues and cancer cell lines. In patient samples, LINC00598 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
