LINC00592

Across TCGA pan-cancer cohorts, LINC00592 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00592’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC00592 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00592 is over-expressed in tumor.

KIRP, COAD, and LUSC are the cancer types where LINC00592 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00592 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.274	<.001	11	view →
COAD	All	II,III,IV	+0.141	<.001	9	view →
LUSC	Male	II,III,IV	+1.077	<.001	8	view →
HNSC	Male	All	+0.741	<.001	6	view →
BLCA	All	IV	+0.597	.011	5	view →
LUAD	All	All	+0.373	<.001	5	view →
CHOL	All	All	+0.474	.005	2	view →
READ	All	All	+0.152	.031	1	view →
THCA	All	All	+0.086	.037	1	view →
LIHC	Male	All	+0.027	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

LINC00592–KIRP

Open the KIRP breakdown →