LINC00575

Across TCGA pan-cancer cohorts, LINC00575 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC00575’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00575 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00575 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

HNSC and LUAD are the cancer types where LINC00575 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00575 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	+0.034	.035	4	view →
LUAD	All	All	−0.032	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LINC00575–HNSC

Open the HNSC breakdown →