LINC00565

Across TCGA pan-cancer cohorts, LINC00565 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC00565’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00565 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00565 is over-expressed in tumor, although a few such as UCEC and PAAD show the opposite, repressed pattern.

KIRC, HNSC, and STAD are the cancer types where LINC00565 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00565 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.167	<.001	8	view →
HNSC	Female	All	+0.380	<.001	7	view →
STAD	All	II,III,IV	+0.178	<.001	6	view →
KIRP	Male	All	+0.158	.013	3	view →
UCEC	All	All	−0.433	.004	2	view →
PAAD	Male	All	−0.335	.049	2	view →
CHOL	All	All	+0.290	.004	2	view →
PRAD	All	All	−0.101	.025	2	view →
BLCA	Male	IV	−0.487	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC00565–KIRC

Open the KIRC breakdown →