Across TCGA pan-cancer cohorts, LINC00563 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC00563’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC00563 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00563 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.
LUAD, LUSC, and KIRC are the cancer types where LINC00563 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00563 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.