Across TCGA pan-cancer cohorts, LINC00554 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC00554’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00554 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00554 is over-expressed in tumor.
KIRC are the cancer types where LINC00554 tumor–normal differential expression is most reproducible.