LINC00550

Across TCGA pan-cancer cohorts, LINC00550 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated LINC00550 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher LINC00550 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00550 expression acts as an unfavorable survival marker, although some lineages such as THCA show a favorable association.

LGG, BRCA, and CESC are the cancer types where LINC00550 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.412	0.762	<.001	36	view →
BRCA	DFS	Tertile	IV	0.175	0.730	.005	36	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
SARC	DFS	Tertile	All	0.198	0.505	.011	30	view →
LIHC	DFS	Tertile	All	0.154	0.533	.018	27	view →
SKCM	OS	Tertile	III,IV	0.608	0.814	.009	15	view →
KIRC	DFS	Quartile	III,IV	0.319	0.506	.011	7	view →
THCA	DFS	Tertile	All	1.000	0.814	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

LINC00550–LGG (DFS)

Open the LGG breakdown →