Across TCGA patient cohorts, LINC00539 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00539-associated genes across cancer lineages are MTND3P16, MIR6857, and MIR3133. Each is linked with LINC00539 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00539-to-partner and partner-to-LINC00539 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00539→partner) and Y-score (partner→LINC00539) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND3P16 →	+0.134	+7.741	<.001	.009	3	1
UCEC	MIR6857 →	+0.837	+5.358	<.001	.006	3	1
UCEC	MIR3133 →	+0.560	+5.133	.001	.008	3	1
UCEC	MIR4698 →	+1.461	+5.031	<.001	.009	3	1
UCEC	OR2AP1 →	+0.138	+5.852	<.001	.003	3	1
UCEC	RNU6-668P →	+1.040	+5.771	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

LINC00539 survival (RNA) · tumor vs normal (RNA) · all LINC00539 data types