LINC00533

Across TCGA pan-cancer cohorts, LINC00533 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC00533’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC00533 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00533 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, KIRP, and KIRC are the cancer types where LINC00533 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00533 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.628	<.001	10	view →
KIRP	All	III,IV	+0.609	.006	5	view →
KIRC	All	All	+0.136	.005	5	view →
KICH	All	All	+0.298	.014	4	view →
BRCA	All	All	−0.029	.008	4	view →
LIHC	All	II,III,IV	+0.156	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LINC00533–THCA

Open the THCA breakdown →