Across TCGA pan-cancer cohorts, LINC00529 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC00529’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC00529 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00529 is over-expressed in tumor.
HNSC are the cancer types where LINC00529 tumor–normal differential expression is most reproducible.