LINC00526

Across TCGA pan-cancer cohorts, LINC00526 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC00526’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC00526 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00526 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and KIRP are the cancer types where LINC00526 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00526 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−1.630	<.001	11	view →
COAD	Male	II,III,IV	−0.932	<.001	10	view →
KIRP	Male	All	−0.694	<.001	8	view →
UCEC	All	All	−1.651	<.001	6	view →
READ	All	All	−1.007	.002	6	view →
BRCA	Female	II,III,IV	−0.734	<.001	6	view →
LUSC	All	All	+0.427	<.001	4	view →
CHOL	All	All	−0.933	<.001	3	view →
BLCA	Male	IV	−1.234	.008	1	view →
LIHC	Female	All	−0.561	.012	1	view →
HNSC	All	III,IV	+0.309	.031	1	view →
THCA	Male	All	−0.290	.005	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC00526–KICH

Open the KICH breakdown →