Q-omics provides the consensus-scored LINC00524 profile across patient tissues and cancer cell-line models. LINC00524 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC00524 is differentially expressed in 12, with the highest sampling consensus in HNSC. Additionally, LINC00524 RNA expression shows 8,342 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, HNSC, and TGCT as cancer lineages where LINC00524 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00524 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00524 survival associations across molecular data types. LINC00524 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00524 RNA expression–survival associations across cancer types. High LINC00524 expression shows unfavorable associations in KIRC, UVM, PAAD, KICH and LUSC, but favorable associations in BRCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC00524 RNA expression.
This table summarizes LINC00524 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00524. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00524 shows lower tumor expression in BLCA and higher tumor expression in HNSC, COAD, KIRC, LUAD and STAD. The HNSC box plot shows higher LINC00524 RNA expression in tumor versus normal tissue (log2 FC = +0.361, t-test p < 0.001).
This table shows molecular features associated with LINC00524 in patient tissues and cancer cell lines. In patient samples, LINC00524 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
