Across TCGA patient cohorts, LINC00523 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00523-associated genes across cancer lineages are TRIM60, NUDT4P2, and RNU6-254P. Each is linked with LINC00523 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00523-to-partner and partner-to-LINC00523 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00523→partner) and Y-score (partner→LINC00523) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRIM60 →	+0.121	+4.473	.001	.005	3	1
UCEC	NUDT4P2 →	+0.089	+4.484	<.001	.009	3	1
UCEC	RNU6-254P →	+0.708	+5.109	<.001	.001	3	1
UCEC	RNU4-56P →	+0.440	+5.582	<.001	.002	3	1
UCEC	RNU6-147P →	+0.422	+4.551	.004	.009	3	1
UCEC	MIR32 →	+0.679	+4.484	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

LINC00523 survival (RNA) · tumor vs normal (RNA) · all LINC00523 data types