LINC00514

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00514 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00514-associated genes across cancer lineages are OR6K6, EIF1AY, and RNA5SP502. Each is linked with LINC00514 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00514-to-partner and partner-to-LINC00514 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6K6 grouped by LINC00514-low versus LINC00514-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00514→partner) and Y-score (partner→LINC00514) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOR6K6 →+0.101+3.621<.001.00431
UCECEIF1AY →+0.029+4.374.001<.00131
UCECRNA5SP502 →+0.630+3.730.007<.00131
UCECRNU6-1082P →+0.439+3.814<.001.00231
UCECRNU6-1 →+0.582+3.100.007.00431
UCECRNU6-206P →+0.275+4.660<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

OR6K6 by LINC00514 expression — UCEC

Box plot of OR6K6 in LINC00514-low vs LINC00514-high samples in UCEC.

Explore this box plot interactively →

Exploration