LINC00513

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00513 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC00513’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LINC00513 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00513 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where LINC00513 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00513 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHMaleII,III,IV−1.473<.00110view →
COADMaleAll+1.224<.0019view →
THCAMaleAll−0.865<.0019view →
LIHCAllAll+0.545<.0017view →
LUSCFemaleAll−0.487<.0016view →
LUADAllAll+0.619.0015view →
BRCAAllIII,IV−0.449.0114view →
STADMaleAll+0.239.0283view →
KIRCMaleAll−0.238.0292view →
HNSCAllIII,IV+0.152.0152view →
CHOLMaleAll+0.695.0471view →
KIRPMaleAll−0.457.0321view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC00513–KICH

Tumor-vs-normal expression box plot for LINC00513 RNA in KICH.

Open the KICH breakdown →

Exploration