long intergenic non-protein coding RNA 511Genealiases: LCAL5 · onco-lncRNA-12
Q-omics provides the consensus-scored LINC00511 profile across patient tissues and cancer cell-line models. LINC00511 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, LINC00511 is differentially expressed in 16, with the highest sampling consensus in LUAD. Additionally, LINC00511 RNA expression shows 18,740 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, LUAD, and UVM as cancer lineages where LINC00511 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00511 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00511 survival associations across molecular data types. LINC00511 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00511 RNA expression–survival associations across cancer types. High LINC00511 expression shows unfavorable associations in KIRC, ACC, LIHC, BRCA, THYM and LUAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for LINC00511 RNA expression.
This table summarizes LINC00511 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00511. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00511 shows lower tumor expression in KICH and higher tumor expression in LUAD, THCA, BLCA, HNSC and LIHC. The LUAD box plot shows higher LINC00511 RNA expression in tumor versus normal tissue (log2 FC = +2.400, t-test p < 0.001).
This table shows molecular features associated with LINC00511 in patient tissues and cancer cell lines. In patient samples, LINC00511 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
