Across TCGA pan-cancer cohorts, LINC00508 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC00508’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00508 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00508 is over-expressed in tumor.
KIRC are the cancer types where LINC00508 tumor–normal differential expression is most reproducible.