LINC00499

Across TCGA patient cohorts, LINC00499 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,743 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00499-associated GO terms across cancer lineages are TOR signaling, Positive regulation of protein kinase activity, and Positive regulation of nervous system development. Each is linked with LINC00499 in more than 11 cancer types. Because this analysis shows association rather than direction, both LINC00499-to-partner and partner-to-LINC00499 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOR signaling grouped by LINC00499-low versus LINC00499-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00499→partner) and Y-score (partner→LINC00499) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	TOR signaling →	+0.080	+0.057	<.001	<.001	3	12
STAD	Positive regulation of protein kinase activity →	+0.066	+0.055	<.001	<.001	3	12
STAD	Positive regulation of nervous system development →	+0.051	+0.056	<.001	<.001	3	11
STAD	Establishment of protein localization to membrane →	+0.085	+0.058	<.001	<.001	3	11
STAD	Microtubule-based transport →	+0.058	+0.053	<.001	<.001	3	11
STAD	Regulation of protein localization to membrane →	+0.077	+0.063	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,743 associations by consensus.

TOR signaling by LINC00499 expression — STAD

Explore this box plot interactively →