LINC00498

Across TCGA patient cohorts, LINC00498 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,197 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00498-associated GO terms across cancer lineages are Negative regulation of apoptotic signaling pathway, Transport along microtubule, and Protein-containing complex localization. Each is linked with LINC00498 in more than 9 cancer types. Because this analysis shows association rather than direction, both LINC00498-to-partner and partner-to-LINC00498 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of apoptotic signaling pathway grouped by LINC00498-low versus LINC00498-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00498→partner) and Y-score (partner→LINC00498) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of apoptotic signaling pathway →	+0.096	+0.086	<.001	<.001	3	10
STAD	Transport along microtubule →	+0.083	+0.083	<.001	<.001	3	10
STAD	Protein-containing complex localization →	+0.075	+0.156	<.001	<.001	3	10
STAD	Receptor metabolic process →	+0.094	+0.077	<.001	<.001	3	10
STAD	Vesicle-mediated transport to the plasma membrane →	+0.093	+0.075	<.001	<.001	3	9
STAD	Polyol metabolic process →	+0.061	+0.100	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,197 associations by consensus.

Negative regulation of apoptotic signaling pathway by LINC00498 expression — STAD

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