LINC00486

Across TCGA patient cohorts, LINC00486 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,175 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LINC00486-associated proteins across cancer lineages are SEMA4D_S833, SPAST, and SIPA1L2_S1244. Each is linked with LINC00486 in more than 2 cancer types. Because this analysis shows association rather than direction, both LINC00486-to-partner and partner-to-LINC00486 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC00486 versus SEMA4D_S833 in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00486→partner) and Y-score (partner→LINC00486) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEMA4D_S833 →	+0.637	+0.118	.002	.003	3	3
LSCC	SPAST →	+0.341	+0.191	<.001	.003	3	3
PDAC	SIPA1L2_S1244 →	+0.728	+0.059	.001	.001	3	3
CCRCC	COPA_S402 →	-0.830	-0.139	.002	<.001	3	3
HNSC	EIF3H →	-0.173	-0.481	<.001	.002	3	3
GBM	VASP →	-0.385	-0.417	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,175 associations by consensus.

LINC00486 vs SEMA4D_S833 — OV

Explore this scatter interactively →