LINC00476

Across TCGA pan-cancer cohorts, LINC00476 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC00476 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher LINC00476 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC00476 expression acts as an unfavorable survival marker, although some lineages such as PAAD and CHOL show a favorable association.

PAAD, ACC, and CHOL are the cancer types where LINC00476 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.515	0.260	<.001	83	view →
ACC	DFS	Median	All	0.250	0.660	<.001	71	view →
CHOL	DFS	Quartile	All	1.000	0.269	.002	31	view →
KIRP	DFS	Median	All	0.904	0.609	.002	30	view →
KIRC	DFS	Median	All	0.714	0.525	.005	20	view →
LAML	DFS	Tertile	All	0.428	0.685	.013	18	view →
MESO	OS	Median	All	0.656	0.357	.019	15	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	12	view →
LGG	OS	Tertile	All	0.952	0.813	<.001	11	view →
LUSC	DFS	Median	III,IV	0.483	0.916	.003	9	view →
READ	OS	Median	All	0.982	0.860	.012	9	view →
BLCA	OS	Tertile	IV	0.202	0.623	.022	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC00476–PAAD (OS)

Open the PAAD breakdown →