LINC00469

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00469 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00469-associated genes across cancer lineages are TERF1P2, RNU6-1082P, and SLCO1B7. Each is linked with LINC00469 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00469-to-partner and partner-to-LINC00469 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TERF1P2 grouped by LINC00469-low versus LINC00469-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00469→partner) and Y-score (partner→LINC00469) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTERF1P2 →+0.105+3.815.005.00931
UCECRNU6-1082P →+0.570+5.136<.001<.00131
UCECSLCO1B7 →+0.227+3.927<.001.00731
UCECRNU6-354P →+0.459+4.223.005.00331
UCECRNU6-767P →+0.619+3.871.002.00631
UCECRNU6-192P →+0.374+4.267.002.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

TERF1P2 by LINC00469 expression — UCEC

Box plot of TERF1P2 in LINC00469-low vs LINC00469-high samples in UCEC.

Explore this box plot interactively →

Exploration