Across TCGA pan-cancer cohorts, LINC00463 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC00463’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where LINC00463 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00463 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD and UCEC are the cancer types where LINC00463 tumor–normal differential expression is most reproducible.