long intergenic non-protein coding RNA 462Genealiases: []
Q-omics provides the consensus-scored LINC00462 profile across patient tissues and cancer cell-line models. LINC00462 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, LINC00462 is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, LINC00462 RNA expression shows 7,553 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight KIRP, KIRC, and ESCA as cancer lineages where LINC00462 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00462 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00462 survival associations across molecular data types. LINC00462 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00462 RNA expression–survival associations across cancer types. High LINC00462 expression shows unfavorable associations in KIRP, ACC, LIHC, SKCM and PAAD, but favorable associations in BRCA. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for LINC00462 RNA expression.
This table summarizes LINC00462 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00462. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00462 shows lower tumor expression in KICH and COAD and higher tumor expression in KIRC, KIRP, LUSC and HNSC. The KIRC box plot shows higher LINC00462 RNA expression in tumor versus normal tissue (log2 FC = +5.000, t-test p < 0.001).
This table shows molecular features associated with LINC00462 in patient tissues and cancer cell lines. In patient samples, LINC00462 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
