Across TCGA patient cohorts, LINC00454 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,004 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00454-associated GO terms across cancer lineages are Microtubule polymerization or depolymerization, Negative regulation of protein catabolic process, and DNA-templated transcription elongation. Each is linked with LINC00454 in more than 10 cancer types. Because this analysis shows association rather than direction, both LINC00454-to-partner and partner-to-LINC00454 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00454→partner) and Y-score (partner→LINC00454) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microtubule polymerization or depolymerization →	+0.080	+0.241	<.001	<.001	3	11
STAD	Negative regulation of protein catabolic process →	+0.061	+0.195	<.001	<.001	3	11
STAD	DNA-templated transcription elongation →	+0.069	+0.211	<.001	<.001	3	10
STAD	Protein polyubiquitination →	+0.062	+0.188	<.001	<.001	3	10
STAD	Negative regulation of kinase activity →	+0.058	+0.205	<.001	<.001	3	10
STAD	Protein folding →	+0.062	+0.185	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,004 associations by consensus.

Exploration

LINC00454 survival (RNA) · tumor vs normal (RNA) · all LINC00454 data types