LINC00452

Across TCGA patient cohorts, LINC00452 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,020 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00452-associated GO terms across cancer lineages are Positive regulation of fibroblast proliferation, Cellular senescence, and Regulation of cell cycle G1/S phase transition. Each is linked with LINC00452 in more than 20 cancer types. Because this analysis shows association rather than direction, both LINC00452-to-partner and partner-to-LINC00452 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of fibroblast proliferation grouped by LINC00452-low versus LINC00452-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00452→partner) and Y-score (partner→LINC00452) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of fibroblast proliferation →	+0.059	+0.089	<.001	<.001	3	21
STAD	Cellular senescence →	+0.061	+0.072	<.001	<.001	3	20
STAD	Regulation of cell cycle G1/S phase transition →	+0.061	+0.076	<.001	<.001	3	19
STAD	Positive regulation of cytoskeleton organization →	+0.060	+0.069	<.001	<.001	3	18
STAD	Negative regulation of mitotic cell cycle phase transition →	+0.061	+0.082	<.001	<.001	3	18
STAD	Positive regulation of stem cell population maintenance →	+0.059	+0.086	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,020 associations by consensus.

Positive regulation of fibroblast proliferation by LINC00452 expression — STAD

Explore this box plot interactively →