Across TCGA patient cohorts, LINC00449 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,203 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LINC00449-associated proteins across cancer lineages are PLCG2, ICAM3, and CTSO. Each is linked with LINC00449 in more than 3 cancer types. Because this analysis shows association rather than direction, both LINC00449-to-partner and partner-to-LINC00449 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00449→partner) and Y-score (partner→LINC00449) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLCG2 →	-0.596	-0.340	<.001	<.001	3	4
GBM	ICAM3 →	-0.670	-0.286	<.001	.002	3	4
UCEC	CTSO →	-0.430	-0.490	.004	.003	3	3
UCEC	IKBKG →	-0.213	-0.405	<.001	<.001	3	3
LSCC	ZNF638_S1401 →	+0.432	+0.240	.003	.001	3	3
LSCC	UTP15 →	+0.280	+0.323	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,203 associations by consensus.

Exploration

LINC00449 survival (RNA) · tumor vs normal (RNA) · all LINC00449 data types