LINC00443

Across TCGA pan-cancer cohorts, LINC00443 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LINC00443 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00443 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC00443 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

KIRC, PAAD, and HNSC are the cancer types where LINC00443 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.710	0.545	<.001	46	view →
PAAD	DFS	Quartile	All	0.150	0.486	.002	22	view →
HNSC	DFS	Tertile	All	0.211	0.360	.002	20	view →
THYM	OS	Tertile	All	0.748	0.986	<.001	18	view →
KIRP	DFS	Median	All	0.618	0.849	.024	16	view →
SKCM	DFS	Tertile	II,III,IV	0.699	0.547	.013	12	view →
UCS	OS	Tertile	IV	0.992	0.447	.024	12	view →
ACC	OS	Tertile	IV	0.344	0.724	.038	12	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
UVM	OS	Tertile	III,IV	0.213	0.691	.045	9	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
OV	OS	Median	III,IV	0.861	0.808	.022	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LINC00443–KIRC (OS)

Open the KIRC breakdown →