LINC00427

Across TCGA patient cohorts, LINC00427 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,085 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LINC00427-associated proteins across cancer lineages are PDS5B, PNISR_S563, and SPART. Each is linked with LINC00427 in more than 3 cancer types. Because this analysis shows association rather than direction, both LINC00427-to-partner and partner-to-LINC00427 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC00427 versus PDS5B in GBM, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00427→partner) and Y-score (partner→LINC00427) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDS5B →	+0.301	+0.609	.007	.004	3	4
OV	PNISR_S563 →	-0.653	-0.465	<.001	<.001	3	4
LSCC	SPART →	+0.250	+0.438	<.001	<.001	3	4
LSCC	PRKAR1A_S83 →	+0.411	+0.713	<.001	<.001	3	4
PDAC	SUPT4H1 →	+0.417	+0.464	.005	.003	3	4
HNSC	RFX5 →	+0.394	+0.621	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,085 associations by consensus.

LINC00427 vs PDS5B — GBM

Explore this scatter interactively →