LINC00426

Across TCGA pan-cancer cohorts, LINC00426 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC00426’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC00426 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00426 is over-expressed in tumor, although a few such as LUSC and BLCA show the opposite, repressed pattern.

KIRC, STAD, and LUSC are the cancer types where LINC00426 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00426 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.673	<.001	10	view →
STAD	All	All	+0.448	.025	4	view →
LUSC	All	II,III,IV	−0.364	.011	4	view →
BLCA	All	III,IV	−0.422	.032	3	view →
LUAD	All	All	+0.355	.001	2	view →
KICH	All	All	−0.244	.019	2	view →
UCEC	All	All	−0.185	.026	2	view →
CHOL	All	All	+0.657	.025	1	view →
COAD	All	IV	−0.407	.039	1	view →
THCA	All	All	−0.257	.041	1	view →
KIRP	All	All	+0.143	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC00426–KIRC

Open the KIRC breakdown →